Dr Stefanie Döll

Administrative Head (Molecular Interaction Ecology)

Research focus


Having studied botany with a focus on plant-environment interactions, I concentrated during my PhD on the regulation of secondary metabolism under biotic and abiotic stress. I investigated the regulation of phenylpropanoid biosynthesis with methods from molecular biology and analytical chemistry. I am specialized in untargeted metabolite profiling with LC-QToF-MS that investigates questions like finding differences between control and stress treatment, mutant and WT or even describes the whole part of the metabolome accessible by this method. During the last years, the analysis of root and leaf exudates from cultivated or wild plant species became the main focus of my work.

ORCID: 0000-0002-0001-8302



Untargeted Metabolite Profiling, LC-QToF-MS, HPLC Secondary/Specialized Metabolism, Phenylpropanoids, Coumarin Biosynthesis, Biotic and Abiotic Stress, Exudates

Short CV


2020 - now     

Scientific employee at the Molecular Interaction Ecology (MIE) research group at the German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig as employee of the Friedrich Schiller University Jena.

Project: “Tree Diversity Interactions: The role of tree-tree interactions in local neighbourhoods in Chinese subtropical forests: Biodiversity effects on tree root exudate metabolomes” part of ITN TreeDi, funded by DFG (GRK 2324) and Chinese Academy of Sciences (CAS) with Dr Steffen Neumann and Dr Alexander Weinhold.

2016 - 2019  

Scientific employee of the Leibniz-Institute of Plant Biochemistry Halle, coordinator of the LC-MS platform of the Metabolomics group, Department of Stress and Developmental Biology.

2012 - 2016    

Senior Scientist at the Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Applied Biochemistry Group, Physiology and Cell Biology Department, German Plant Phenotyping Network (DPPN).


PhD defence at the Martin-Luther-University Halle-Wittenberg: ”Studies on Scopolin and Scopoletin -Stress-Induced Accumulation and Regulatory Elements" (Doctor rerum naturalium).

2007 - 2012   

PhD researcher at the Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Applied Biochemistry Group, Physiology and Cell Biology Department.

2005 - 2006    

Scientific employee at the Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Genebank Documentation, Genebank.


Defence of the Diploma thesis "Reproductive biology of the three understorey plants Justicia rusbyi (Acanthaceae), Gloxinia sylvatica and Gloxinia purpurascens (Gesneriaceae) in a tropical mountain forest in eastern Bolivia" at the Martin-Luther Universität Halle-Wittenberg, Faculty of Biology, Institute for Geobotany and Population Ecology.


Research stay at the biological station “Los Volcanes”, Santa Cruz, Bolivia.

1998 - 2004    

Study of Biology at Martin-Luther-University Halle-Wittenberg.

Selected Publications:

Selected publications


Serag, A., Baky, M.H., Doll, S. and Farag, M.A. (2020) UHPLC-MS metabolome based classification of umbelliferous fruit taxa: a prospect for phyto-equivalency of its different accessions and in response to roasting. Rsc Advances, 10, 76-85.

Peters, K.; Treutler, H., Döll, S.; Kindt, A.; Hankemeier, T.; Neumann, S. Chemical Diversity and Classification of Secondary Metabolites in Nine Bryophyte Species Metabolites 2019, 9(10), 222; doi.org/10.3390/metabo9100222.

Döll, S.; Arens, N.; Mock, H. Liquid Chromatography and Liquid Chromatography–Mass Spectrometry of Plants: Techniques and Applications (Meyers, R. A., ed.). (2019) ISBN: 9780470027318 DOI: 10.1002/9780470027318.a9912.pub2.

Matern, A.; Böttcher, C.; Eschen-Lippold, L.; Westermann, B.; Smolka, U.; Döll, S.; Trempel, F.; Aryal, B.; Scheel, D.; Geisler, M.; Rosahl, S. A substrate of the ABC transporter PEN3 stimulates bacterial flagellin (flg22)-induced callose deposition in Arabidopsis thaliana J Biol Chem 294, 6857-6870, (2019) DOI: 10.1074/jbc.RA119.007676

Döll, S.; Kuhlmann, M.; Rutten, T.; Mette, M. F.; Scharfenberg, S.; Petridis, A.; Berreth, D.-C.; Mock, H.-P. Accumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex Plant J 93, 431-444, (2018) DOI: 10.1111/tpj.13797

Petridis A, Döll S., Nichelmann L, Bilger W, Mock HP: Arabidopsis thaliana G2-LIKE FLAVONOID REGULATOR and BRASSINOSTEROID ENHANCED EXPRESSION1 are low-temperature regulators of flavonoid accumulation. New Phytologist (2016), doi: 10.1111/nph.13986.

Arens N, Döll S., Mock HP (2015): The reproducibility of liquid chromatography separation technology and its potential impact on large scale plant metabolomics experiments. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 991, 41-45.

Schmid NB, Giehl RF, Döll S., Mock HP, Strehmel N, Scheel D, Kong X, Hider RC, von Wirén N (2014) Feruloyl-CoA 6'-Hydroxylase1-Dependent Coumarins Mediate Iron Acquisition from Alkaline Substrates in Arabidopsis. Plant Physiol 164: 160-172

Döll S., Hensen I, Schmidt-Lebuhn AN, Kessler M (2007). "Pollination ecology of Justicia rusbyi (Acanthaceae), a common understory plant in a tropical mountain forest in eastern Bolivia." Plant Species Biology 22(3): 211-216.

iDiv publications


Farag, M. A., Kabbash, E. M., Mediani, A., Döll, S., Esatbeyoglu, T. and Afifi, S. M.

(2022): Comparative Metabolite Fingerprinting of Four Different Cinnamon Species Analyzed via UPLC–MS and GC–MS and Chemometric Tools. Molecules

Weinhold, A., Döll, S., Liu, M., Schedl, A., Pöschl, Y., Xu, X., Neumann, S. and van Dam, N. M.

(2021): Tree species richness differentially affects the chemical composition of leaves, roots and root exudates in four subtropical tree species. Journal of Ecology

S. Döll, R. Djalali Farahani-Kofoet, R. Zrenner, A. Henze, K. Witzel

(2021): Tissue-specific signatures of metabolites and proteins in asparagus roots and exudates. Horticulture Research
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Friedrich Schiller University Jena

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